Detalhe da pesquisa
1.
Fibrosis induced by resident macrophages has divergent roles in pancreas inflammatory injury and PDAC.
Nat Immunol
; 24(9): 1443-1457, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37563309
2.
Structural insights into Ubr1-mediated N-degron polyubiquitination.
Nature
; 600(7888): 334-338, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34789879
3.
Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression.
Immunity
; 47(2): 323-338.e6, 2017 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28813661
4.
Thioester-Assisted Sortase-A-Mediated Ligation.
Angew Chem Int Ed Engl
; 61(28): e202201887, 2022 07 11.
Artigo
Inglês
| MEDLINE | ID: mdl-35514243
5.
Potassium channel selectivity filter dynamics revealed by single-molecule FRET.
Nat Chem Biol
; 15(4): 377-383, 2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30833778
6.
Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression.
Immunity
; 47(3): 597, 2017 09 19.
Artigo
Inglês
| MEDLINE | ID: mdl-28930665
7.
Chemical Synthesis of Activity-Based E2-Ubiquitin Probes for the Structural Analysis of E3 Ligase-Catalyzed Transthiolation.
Angew Chem Int Ed Engl
; 60(31): 17171-17177, 2021 07 26.
Artigo
Inglês
| MEDLINE | ID: mdl-34021957
8.
An E1-Catalyzed Chemoenzymatic Strategy to Isopeptide-N-Ethylated Deubiquitylase-Resistant Ubiquitin Probes.
Angew Chem Int Ed Engl
; 59(32): 13496-13501, 2020 08 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32346954
9.
Cysteine-Aminoethylation-Assisted Chemical Ubiquitination of Recombinant Histones.
J Am Chem Soc
; 141(8): 3654-3663, 2019 02 27.
Artigo
Inglês
| MEDLINE | ID: mdl-30758956
10.
Efficient Semi-Synthesis of Atypical Ubiquitin Chains and Ubiquitin-Based Probes Forged by Thioether Isopeptide Bonds.
Chemistry
; 25(72): 16668-16675, 2019 Dec 20.
Artigo
Inglês
| MEDLINE | ID: mdl-31625216
11.
One-pot multi-segment condensation strategies for chemical protein synthesis.
Org Biomol Chem
; 17(4): 727-744, 2019 01 23.
Artigo
Inglês
| MEDLINE | ID: mdl-30566163
12.
Ligation of Soluble but Unreactive Peptide Segments in the Chemical Synthesis of Haemophilus Influenzae DNA Ligase.
Angew Chem Int Ed Engl
; 58(35): 12231-12237, 2019 08 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31250514
13.
A role for glutamine 183 in the folate oxidative half-reaction of methylenetetrahydrofolate reductase from Escherichia coli.
Arch Biochem Biophys
; 642: 63-74, 2018 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29407039
14.
Salinomycin-loaded lipid-polymer nanoparticles with anti-CD20 aptamers selectively suppress human CD20+ melanoma stem cells.
Acta Pharmacol Sin
; 39(2): 261-274, 2018 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-29388568
15.
Hnf4 activates mimetic-cell enhancers to recapitulate gut and liver development within the thymus.
J Exp Med
; 220(10)2023 10 02.
Artigo
Inglês
| MEDLINE | ID: mdl-37399024
16.
A bifunctional molecule-assisted synthesis of mimics for use in probing the ubiquitination system.
Nat Protoc
; 18(2): 530-554, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36323865
17.
Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity.
Cancer Cell
; 41(6): 1073-1090.e12, 2023 06 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37236195
18.
Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy.
J Exp Med
; 220(6)2023 06 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36951731
19.
Combination TIGIT/PD-1 blockade enhances the efficacy of neoantigen vaccines in a model of pancreatic cancer.
Front Immunol
; 13: 1039226, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36569934
20.
Stromal Reprogramming by FAK Inhibition Overcomes Radiation Resistance to Allow for Immune Priming and Response to Checkpoint Blockade.
Cancer Discov
; 12(12): 2774-2799, 2022 12 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36165893